Recently, a study titled “Validation and implementation of Planova™ BioEX virus filters in the manufacture of a new liquid intravenous immunoglobulin in China” was published on Biologicals (Ma et al, 2018). The study reports the development and optimization of a manufacturing-scale virus removal step for intravenous immunoglobulin (IVIG) using Planova™ BioEX.
From the results, it was demonstrated that improved viral safety of IVIG can be assured by implementing a virus removal step using Planova™ BioEX to ensure effective parvovirus clearance. Furthermore, excellent protein recovery was achieved and there was no detectable impact on product biochemical properties.
The article can be accessed for free for a limited period of time – anyone clicking on the link below before May 29, 2018 will be taken directly to the final version of the article on ScienceDirect. No sign up, registration or fees are required – you can simply click and read here.
We encourage you to use the above link to download a copy and learn more through a case study on how Planova™ BioEX can help you assure an improved viral safety for your products. After May 29, 2018, the article will be available for request on our Library Page. You can also request a copy of other articles demonstrating the use of Planova™ filters in the manufacture of various biotherapeutic products via our Library Page.