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Review paper on filter made of cuprammonium regenerated cellulose for virus removal

Jan 26, 2022

January 26, 2022
Asahi Kasei Medical Co., Ltd.
Asahi Kasei Medical Corporation is pleased to announce the review paper on the filter made of cuprammonium regenerated cellulose for virus removal has been published in the scientific journal Cellulose.

Asahi Kasei Medical is the global market leader in virus filtration, with its Planova™ filters having an unrivaled 30-year history of trusted use in the production of biotherapeutics. We aim to provide "Assurance Beyond Expectation" to ensure product safety and manufacturing efficiency for therapeutics within the biopharmaceutical industry in the form of innovative yet exceptionally reliable bioprocess consumables, equipment and related scientific support, and biosafety testing services.

Planova™ has made it possible to separate proteins and viruses, making virus removal filters (VFs) one of the critical modern technologies to assure virus safety of biological products. It has also become an indispensable technology for the future. This paper outlines the emergence of VF and their essential roles in the purification process of biological products, requirements for VF, phase separation studies of cuprammonium cellulose solutions, comparison between Planova™ and other regenerated cellulose flat membranes made from other cellulose solutions, and the development of Planova™ in the last three decades. The superior properties of Planova™ can be attributed to its highly interconnected three-dimensional network structure.

By strength in a deep understanding of technologies of phase separation, advanced control technology of membrane structure, and advanced characterization analysis of membranes using viruses, proteins, etc. We believe that VF can contribute to the future response to new needs for manufacturing biological products and utilization of VF for new therapeutics such as cell and gene therapy and regenerative medicines.

Asahi Kasei Medical will continue to contribute to the greater safety of biotherapeutic products by developing high-quality and high-performance products.

The article "Filter made of cuprammonium regenerated cellulose for virus removal: a mini-review" has been published in Cellulose on 23 November 2021. On publication, the paper has been freely available online at​