Products & Services BioOptimal™ MF-SL Microfilters
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Easy and Effective Clarification Made Possible
BioOptimal MF-SL is a hollow fiber microfilter that utilizes an efficient filtration mechanism based on size exclusion and tangential flow filtration. These two aspects allow the filter to smoothly and effectively separate the contents of a solution.
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Applications
Process simplification
BioOptimal MF-SL is able to clarify solutions quickly and completely in a single processing step. Therefore, it simplifies the cell culture clarification process and makes it more cost-effective by eliminating the needs for large investments like centrifuges and expensive disposable items like other depth filters.
Features
Key Features
- Low TMP (Trans Membrane Pressure)
- High flux, short filtration time
- High protein permeability & recovery rate
- Very low permeate turbidity, less bioburden
- Low pressure stress at filtration process
Basic Information
Tangential Flow Filtration:
The feed fluid flow across the membrane surface creates a sweeping action, preventing quick fouling and extending filtration duration.
Application
Removal of cells from batch culture
TFF-Perfusion cell culture
Monoclonal Antibody (mAb) is one of the main focus categories in biopharmaceuticals. There are several types of cell culture systems such as fed-batch and perfusion culture. Although conventional batch systems are widely accepted in the current process, perfusion based cell culture systems offer the potential to greatly increase cell density and productivity for a long term periods. It is widely accepted that hollow fiber works as a cell separation device in perfusion culture.Specifications
Material Specifications
| Pore size (μm) | 0.4 |
|---|---|
| Hollow fiber ID (mm) | 1.4 |
| Hollow fiber material | Polysulfone |
| Housing | Polysulfone |
Ordering information
Catalog Numbers
| Catalog Number | Effective Membrane Surface Area Size |
|---|---|
| MFSL0005 | 0.005 m² |
| MFSL0190 | 0.19 m² |
| MFSL1000 | 1 m² |
| MFSL8000 | 8 m² |
